06.05.2008 at 08:00
- Category:
Cancer and Oncology
Researchers detail in 'Cigarette smoking and prostate cancer-specific mortality following diagnosis in middle-aged men,' new data in prostate cancer. "The aim of this study was to examine associations of smoking at the time of diagnosis with the risk of prostate cancer death in a population-based cohort of men with prostate cancer. Data were from 752 prostate cancer patients aged 40-64 years, who were enrolled in a case-control study and under long-term follow-up for mortality," scientists writing in the journal Cancer Causes and Control report.
"Cox proportional hazards models were used to estimate hazard ratios (HR) and 95% confidence intervals (CI) for associations between smoking and prostate cancer-specific and other cause mortality. Compared to never smoking, smoking at the time of diagnosis was associated with a significant increase in risk of prostate cancer-specific mortality. After controlling for demographic characteristics, Gleason grade, stage at diagnosis, and primary treatment, the HR was 2.66 (95% CI: 1.10-6.43)," wrote Z. Gong and colleagues, Fred Hutchinson Cancer Research Center, Division of Public Health Sciences.
The researchers concluded: "Smoking at the time of diagnosis, independent of key clinical prognostic factors, is associated with an increased risk of prostate cancer death."
Gong and colleagues published their study in Cancer Causes and Control (Cigarette smoking and prostate cancer-specific mortality following diagnosis in middle-aged men. Cancer Causes and Control, 2008;19(1):25-31).
Additional information can be obtained by contacting Z. Gong, Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, 1100 Fairview Avenue N, Seattle, WA 98109-1024 USA..
The publisher of the journal Cancer Causes and Control can be contacted at: Kluwer Academic Publ, Van Godewijckstraat 30, 3311 Gz Dordrecht, Netherlands.
Copyright 2008, Disease Risk Factor Week via NewsRx.com
